On the Minnesota HCQ trial...
— James Todaro, MD (@JamesTodaroMD) June 4, 2020
There were serious design flaws that include lack of PCR testing, powered for >50% efficacy, survey based follow-up, etc...
...most due to a budget of only ~$100k.
It's unbelievable that funding for well-designed RCTs on HCQ is still this scarce.